Extramammary Paget’s disease
نویسندگان
چکیده
Extramammary Paget’s disease is an uncommon cutaneous adenocarcinoma, characterized by glandular differentiation and an insidious course. The condition may or may not be associated with an underlying adnexal or visceral malignancy. Because of its rarity, the pathogenesis is unclear, and standardization of treatment is lacking. The diagnosis is made histopathologically, and management is based on wide surgical excision. Long-term follow-up is essential to exclude a recurrence of the disease and monitor the patient for an underlying or associated cancer. Here, we report a case of this rare disorder involving the perianal region and briefly review the available literature. This case report draws attention to extramammary Paget’s disease, which should be considered in the differential diagnosis of perianal disorders.
منابع مشابه
Concurrence of Primary Cutaneous Extra Mammary Paget’s Disease and Squamous Cell Carcinoma in situ of Vulva: A Case Report
Extramammary Paget’s disease and vulvar intraepithelial neoplasia are common lesions of vulve, but synchronous occurrence is rare in a same location. Herein we describe a concurrence of primary cutaneous extra mammary Paget’s disease and squamous cell carcinoma in situ of vulva in an Iranian women. A 59 year old woman, initially presented to Kosar teaching hospital gynecology clinic April 2017 ...
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Received October 2008 Accepted February 2009 INTRODUCTION Extramammary Paget’s disease is a condition morphologically similar to Paget’s disease in the breast, but occurs outside the breast. It is an uncommon condition as compared to its mammary counterpart. It most commonly affects the vulva, less commonly the male genital area or the perianal area.(1,2) To the best of our knowledge, extramamm...
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Ever since Sir James Paget first described the disease of the nipple named after him and remarked that he had seen a lesion clinically resembling it on the glans penis, followed by cancer, reputed cases of extramammary Paget’s disease have been sporadically reported and their nature discussed. The debate has been ancillary to the related question of the nature of Paget’s disease, which is still...
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